About vulgaris type disorder of cornification

What is vulgaris type disorder of cornification?

In ichthyosis vulgaris, the skin cells are produced at a normal rate, but they do not shed normally at the surface of the outermost layer of skin (stratum corneum) and are not shed as quickly as they should be. The result is a build-up of scale. Fine scales usually develop on the back and over muscles near the joints, such as an elbow or knee (extensor muscles). Ichthyosis is usually most common and severe over the lower legs.

What are the symptoms for vulgaris type disorder of cornification?

Scaling of skin symptom was found in the vulgaris type disorder of cornification condition

Ichthyosis vulgaris is characterized by Dry skin with small scales in a color range from white to dirty gray or brown.

Ichthyosis vulgaris slows your skin's natural shedding process. This causes chronic, excessive buildup of the protein in the upper layer of the skin (keratin). Symptoms include:

  • Dry, scaly skin
  • Tile-like, small scales
  • White, gray or brown scales, depending on skin color
  • Flaky scalp
  • Deep, painful cracks in your skin

The scales usually appear on your elbows and lower legs and may be especially thick and dark over your shins. Most cases of ichthyosis vulgaris are mild, but some can be severe. The severity of symptoms may vary widely among family members who have the condition.

Symptoms usually worsen or are more pronounced in cold, dry environments and tend to improve or even resolve in warm, humid environments.

What are the causes for vulgaris type disorder of cornification?

Ichthyosis vulgaris is commonly caused by a genetic mutation that's inherited from one or both parents. Children who inherit a defective gene from just one parent have a milder form of the disease. Those who inherit two defective genes have a more severe form of ichthyosis vulgaris. Children with the inherited form of the disorder usually have normal skin at birth, but develop scaling and roughness during the first few years of life.

If genetic abnormalities aren't responsible for ichthyosis, it's referred to as acquired ichthyosis. It's usually associated with other diseases, such as cancer, thyroid disease or HIV/AIDS.

What are the treatments for vulgaris type disorder of cornification?

Ichthyosis vulgaris doesn't have a known cure, so the goal of treatment is to manage the condition

What are the risk factors for vulgaris type disorder of cornification?

Vulgaris type disorder of cornification is an inherited skin disorder in which dead skin cells accumulate on a thick dry scale, on your skin’s surface. It is also called fish skin disease. It is usually present at birth or starts showing signs in early childhood. One should be careful as sometimes the condition goes untreated because it is confused with dry skin.

Some cases are often mild but might get severe over time. There has been no cure for this condition and all the treatments work around controlling the condition.

1. There is a risk of other skin conditions like eczema, which are associated with this one.
2. As it is a genetic condition, there is a risk that the condition is severe if there are two genes passed to the child rather than one.
3. If it's not a genetic condition and it seems to have been an acquired one then the person runs the risk of it being the symptoms of some other diseases like thyroid cancer or HIV AIDS.
4. People with this condition might suffer from excess sweating which inhibits cooling.
5. As the person has dead skin cells, there is a risk of skin splitting and cracking which might lead to skin infections for the person.

6. One has to take extra care as the symptoms of the condition show after early age and not directly at birth.

Symptoms
Scaling of skin,Face is affected, the scaling is usually limited to the cheeks and forehead,Skin on the palms of the hands and soles of the feet is thickened and may have exaggerated lines
Conditions
A build-up of scale,Fine scales usually develop on the back and over muscles near the joints, such as an elbow or knee (extensor muscles),Ichthyosis is usually most common and severe over the lower legs
Drugs
Moisturizers containing urea or glycerol,Lotions containing alpha-hydroxy acids

Is there a cure/medications for vulgaris type disorder of cornification?

  • Exfoliating creams and ointments. Prescription creams and ointments containing alpha hydroxy acids, such as lactic acid and glycolic acid, help control scaling and increase skin moisture.
  • Oral medication. Your doctor may prescribe vitamin A-derived medications called retinoids to reduce the production of skin cells. Side effects from the medication may include eye and lip inflammation, bone spurs and hair loss.

    Retinoids may cause birth defects. Women considering retinoid therapy should be sure they are not pregnant before starting the medication — and use effective birth control while taking retinoids.

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